What is Palmitoyl Tripeptide-1?
Palmitoyl Tripeptide-1 is a synthetic peptide used in anti-aging skincare. It is one of two peptides combined to make Matrixyl 3000, a well-known peptide blend developed by Sederma; the other is palmitoyl tetrapeptide-7. On its own, palmitoyl tripeptide-1 is designed to signal skin cells to produce more collagen, the protein that gives skin its structure and firmness.
Source
|
Found in |
Synthetic peptide (INCI name: Palmitoyl Tripeptide-1) |
|
Origin |
Lab-made peptide, one component of the Matrixyl 3000 blend developed by Sederma |
Top features and benefits
|
Supports collagen production |
Helps smooth the look of fine lines |
Supports firmer-looking skin |
|
Often used alongside palmitoyl tetrapeptide-7 |
Generally well tolerated |
Suitable for daily use in serums and creams |
How Does It Work?
Palmitoyl tripeptide-1 works as a signaling molecule. It mimics a small fragment of collagen that skin naturally produces when it is repairing or remodeling itself, and this fragment tells fibroblasts, the cells responsible for making collagen, to increase their output. More collagen production is associated with firmer, more supported-looking skin over time.
It is rarely used entirely on its own in commercial skincare. It is most often paired with palmitoyl tetrapeptide-7 as the two-peptide blend known as Matrixyl 3000, since the two peptides are generally described as targeting collagen production and the skin's inflammatory response together, rather than one mechanism alone.