What is Palmitoyl Tetrapeptide-7?
Palmitoyl Tetrapeptide-7 is a synthetic peptide used in anti-aging skincare. It is one of two peptides combined to make Matrixyl 3000, alongside palmitoyl tripeptide-1. While its partner peptide is mainly associated with signaling collagen production, palmitoyl tetrapeptide-7 is more specifically studied for its role in calming the low-level inflammation in skin that can accelerate visible aging over time.
Source
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Found in |
Synthetic peptide (INCI name: Palmitoyl Tetrapeptide-7) |
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Origin |
Lab-made peptide, one component of the Matrixyl 3000 blend developed by Sederma |
Top features and benefits
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May help calm the skin's inflammatory response |
Supports the look of firmer, smoother skin |
Often used alongside palmitoyl tripeptide-1 |
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Generally well tolerated |
Suitable for daily use in serums and creams |
Studied as part of the wider Matrixyl 3000 peptide category |
How Does It Work?
Palmitoyl tetrapeptide-7 is thought to work by helping regulate interleukin-6, a signaling molecule the body produces during inflammation. Chronic, low-grade inflammation in skin, sometimes called inflammaging, is one of the processes linked to visible signs of aging like sagging and loss of firmness. By helping calm this inflammatory signaling, palmitoyl tetrapeptide-7 is designed to support a calmer, more resilient-looking complexion alongside the collagen-focused benefits of its partner peptide.
It is almost always used in combination with palmitoyl tripeptide-1 as the Matrixyl 3000 blend, rather than as a standalone ingredient, which is part of why the two are generally discussed together in skincare research and marketing.